Immunomodulation: Causes & Reasons - Symptoma Great Britain

Possible Causes for Immunomodulation

Immunomodulating drugs modify the action of the body's immune system, decreasing its activity. [msdmanuals.com]

People whose symptoms return when prednisone is decreased are sometimes given an immunomodulating drug ( azathioprine or mercaptopurine ). [merckmanuals.com]

Moreover, a combination of immunomodulator and anti-TNF therapy is sometimes helpful. [msdmanuals.com]

Pediatric Ulcerative Colitis

This review will discuss the classical treatments for children with ulcerative colitis, including 5-aminosalicylates, corticosteroids, thiopurine immunomodulators, and calcineurin [jhu.pure.elsevier.com]

A Kaplan–Meier analysis found that 73% of thiopurine immunomodulator–treated children were likely to remain free of rescue therapy at 1 year. [ncbi.nlm.nih.gov]

Keywords: 5-aminosalicylates, anti-tumor necrosis factor-α agents, corticosteroids, cyclosporine, inflammatory bowel disease, thiopurine immunomodulators This work is published [dovepress.com]

Ulcerative Colitis

It is unclear what causative role systemic immunomodulators play in predisposing UC patients to proximal HSIL. [ncbi.nlm.nih.gov]

KEYWORDS: Crohn’s disease of the pouch; Crohn’s disease-like condition of the pouch; Ileal-anal anastomosis; anti-TNF; immunomodulator [ncbi.nlm.nih.gov]

Immunomodulator initiation by 3 months did not reduce risk of colectomy at 1 year. [ncbi.nlm.nih.gov]

Infantile-Onset Pompe Disease

[…] evidence on the management of IOPD with immunomodulation protocol and ERT in this Gulf region. [ncbi.nlm.nih.gov]

Based on existing literature, immunomodulation therapy may be effective in treating IOPD patients. [ncbi.nlm.nih.gov]

However, a dose increment to 40 mg/kg (EOW [off-label]) plus immunomodulation is suggested if poor outcomes are noted. [ncbi.nlm.nih.gov]

Duodenal Crohn Disease

It can be a useful bridge to immunomodulator therapy such as azathioprine and MTX. [healio.com]

The consultant/authors clearly state their approach to important issues, such as the duration of immunomodulator and of anti-TNF-a use and the options for managing isolated [books.google.com]

Treatment is with 5-aminosalicylic acid, corticosteroids, immunomodulators, anticytokines, antibiotics, and often surgery. [merckmanuals.com]

Pediatric Crohn Disease

Durability of response is increased by concomitant immunomodulation. [ncbi.nlm.nih.gov]

Baseline severity and early immunomodulation were similar in both groups. [ncbi.nlm.nih.gov]

Further data are required on the efficacy and safety of methotrexate as an alternative immunomodulator. [ncbi.nlm.nih.gov]

Ulcerative Proctitis

Rarely ulcerative proctitis is refractory to topical therapy and in these instances systemic corticosteroids, antibiotics, immunomodulators, or surgery is required. [ncbi.nlm.nih.gov]

After re-assessment, chronically active patients refractory or intolerant to 5-ASAs and corticosteroids may require immunomodulators or biological therapy. [ncbi.nlm.nih.gov]

Immunomodulators have an important role in individuals with glucocorticoid dependent or glucocorticoid refractory disease. [ncbi.nlm.nih.gov]

Atopic Keratoconjunctivitis

[…] options for AKC is reviewed and presented as a stepwise, multidisciplinary approach that involves the allergist/immunologist's medical interventions of topical and systemic immunomodulating [ncbi.nlm.nih.gov]

Topical immunomodulators such as tacrolimus have revolutionized the treatment of atopic dermatitis. [ncbi.nlm.nih.gov]

Cyclosporin A is an immunomodulator that specifically inhibits T lymphocytes by blocking the expression of the interleukin-2 receptor. [clinicaltrials.gov]

Pouchitis

After failure to respond to antibiotics, aminosalicylates and immunomodulators such as azathioprine and 6-mercaptopurine (6-MP), all patients were treated with infliximab. [ncbi.nlm.nih.gov]

Patients with CARP often require alternative medical approaches to routine antibiotics, including the use of oral or topical mesalazine, corticosteroids, and sometimes immunomodulators [ncbi.nlm.nih.gov]

Pouchitis can progress into an 'IBD-like' condition, requiring anti-inflammatory, immunomodulator or even biological therapy. [ncbi.nlm.nih.gov]

Inflammatory Bowel Disease

Immunomodulators continue to have a place in the treatment of inflammatory bowel disease. [ncbi.nlm.nih.gov]

However, the risk of NAFLD in IBD patients who receive different medical treatments including glucocorticoids, immunomodulators, and tumor necrosis factor-α inhibitors remains [ncbi.nlm.nih.gov]

In Crohn's disease, a combination of immunomodulator and biologic drugs seem to be particularly effective. [onhealth.com]

Pityriasis Lichenoides et Varioliformis Acuta

In more recent years concerns raised about their side effect profile has led to the increased use of nonsteroidal topical immunomodulators. [dermnetnz.org]

If treatment is necessary, recommended therapies may include oral antibiotics, sun exposure, topical steroids, immunomodulators (medications used to help regulate or normalize [rarediseases.info.nih.gov]

Topical immunomodulators such as tacrolimus or pimecrolimus. Tacrolimus ointment applied twice daily has been used successfully to treat patients with PLC. [dermnetnz.org]

Cryoglobulinemic Vasculitis

We report one patient with type-1 cryoglobulinemic vasculitis and skin ulcers that had remained active despite treatment with a variety of immunomodulating drugs including [ncbi.nlm.nih.gov]

The development of SLE during therapy with IFN-alpha could be due to direct immunomodulation by IFN-alpha, and review of experimental data and prior case reports suggests [ncbi.nlm.nih.gov]

Previous treatments failed to control the main signs of vasculitis; these were either HCV (n = 37) or immunomodulating treatments. [ncbi.nlm.nih.gov]

Pityriasis Lichenoides

Treatment options are based on case series-reports, and anecdotes, and include topical corticosteroids, topical immunomodulators, systemic antibiotics (tetracycline, erythromycin [ncbi.nlm.nih.gov]

In more recent years concerns raised about their side effect profile has led to the increased use of nonsteroidal topical immunomodulators. [dermnetnz.org]

Aggressive treatment with immunosuppressant and/or immunomodulating agents as well as intensive supportive care are recommended for FUMHD. [ncbi.nlm.nih.gov]

Eczema

Treatment options such as topical steroids and topical immunomodulators are used initially. [health.ucdavis.edu]

Topical immunomodulators are substances that help to regulate the immune system are used sometimes when eczema is hard to manage. [everydayhealth.com]

Topical Steroids and Immunomodulators Topical corticosteroids and topical immunomodulators are the main treatments for eczema. [pediatrust.com]

Chronic Lichenoid Pityriasis

In more recent years concerns raised about their side effect profile has led to the increased use of nonsteroidal topical immunomodulators. [dermnetnz.org]

Topical immunomodulators such as tacrolimus or pimecrolimus. Tacrolimus ointment applied twice daily has been used successfully to treat patients with PLC. [dermnetnz.org]

Colonic Crohn Disease

Traditionally, it is typically used for patients who are intolerant or refractory to thiopurine immunomodulators. [clinicaladvisor.com]

Treatment includes prevention of infectious complications and immunomodulation. However, a standard strategy is not yet defined. [acgcasereports.gi.org]

In order to maintain control of the disease, aminosalicylates or immunomodulators are used on a long-term basis. [ccrcfw.com]

Stiff-Person Syndrome

Although a number of immunomodulating therapies significantly improve the patients' symptoms, the exact pathogenic mechanisms remain unclear. [ncbi.nlm.nih.gov]

Many patients respond to treatment with immunomodulating therapy. [ncbi.nlm.nih.gov]

Nevertheless, evidence is emerging to suggest that SMS/SLS/PERM are manifestations of an immune-mediated chronic encephalomyelitis and immunomodulation is an effective therapeutic [ncbi.nlm.nih.gov]

Atopic Dermatitis

Current Treatment Options in Allergy", keywords = "Atopic dermatitis, Atopic eczema, Treatment, Therapy, Systemic treatment, Systemic therapy, Immunosuppressive therapy, Immunomodulation [pure.au.dk]

Although they are not approved by the US Food and Drug Administration (FDA), some systemic immunomodulating agents are used for recalcitrant AD, but patients must be monitored [ncbi.nlm.nih.gov]

Topical immunomodulator (TIMs). Topical immunomodulators are a new class of drugs for the treatment of eczema. [web.archive.org]

Neuralgic Amyotrophy

Neuralgic amyotrophy in the lower extremities is rare, but awareness of this disorder helps us avoid unnecessary surgical investigations and leads to possible treatment with immunomodulative [pubmed.ncbi.nlm.nih.gov]

As the presumed mechanism of pathogenesis is immune-mediated, most therapies center on immunomodulation such as corticosteroids, IVIG, and PLEX. [ncbi.nlm.nih.gov]

Partial but rapid recovery from paralysis after immunomodulation during early stage of neuralgic amyotrophy. Nakajima M, Fujioka S, Ohno H, Iwamoto K. [ncbi.nlm.nih.gov]

Inflammatory Bowel Disease Type 1

KEYWORDS: Crohn’s disease of the pouch; Crohn’s disease-like condition of the pouch; Ileal-anal anastomosis; anti-TNF; immunomodulator [ncbi.nlm.nih.gov]

We critically review the evidence for established (5-aminosalicylic acid compounds, corticosteroids, immunomodulators, calcineurin inhibitors) and emerging novel therapies [ncbi.nlm.nih.gov]

Rifaximin could exert, when appropriate, a synergic effect with immunomodulators in IBD, acting on both the microbial and the immunological sides of gut barrier impairment [ncbi.nlm.nih.gov]

Necrobiosis Lipoidica Diabeticorum

[…] blood flow enhancers – aspirin, pentoxyphylline, dipyridamole Corticosteroids – topical and intralesional Wound healing enhancers – topical collagen gel, hyperbaric oxygen Immunomodulation [myfootshop.com]

Immunomodulating drugs; however, these have varying levels of success. -Antiplatelet treatment seems logical, but controlled trials have had different results. [almawiclinic.com]

[…] teams. 4 A recent case-based review of the literature listed the following as treatment options: cutaneous blood flow enhancers, steroid therapy, wound healing enhancers, immunomodulation [woundsresearch.com]

Hepatosplenic Lymphoma

Immunomodulators might need to be avoided after infliximab therapy, and alternative treatments considered. [mja.com.au]

HSTCL in IBD patients on immunomodulators with or without anti-TNF (p 11 ]. [omicsonline.org]

[…] disease control. 5 With the advent and success of antitumour necrosis factor (TNF) and other biological therapies, investigators have sought to define the place of concomitant immunomodulator [gut.bmj.com]

Ileal Crohn Disease

Treatment is with 5-aminosalicylic acid, corticosteroids, immunomodulators, anticytokines, antibiotics, and often surgery. [merckmanuals.com]

They tend to be divided into two groups: Immunomodulators These are medicines that modify and suppress the immune system. [patient.info]

Both immunomodulators and biological agents have side effects, but these side effects are rare. [health.clevelandclinic.org]

Neuromuscular Junction Disorder

Fortunately, a wide range of symptomatic treatments, immunosuppressive drugs, or other immunomodulating therapies is available. [ncbi.nlm.nih.gov]

[…] cochlear implant * Epilepsy: antiepileptic drugs, deep brain stimulation, and vagus nerve stimulation *Involuntary movements: deep brain stimulation * Multiple sclerosis: immunomodulators [books.google.de]

Pityriasis Alba

The provider may recommend the following treatments: Moisturizer Mild steroid creams Medicine, called immunomodulators, applied to the skin to reduce inflammation Treatment [nlm.nih.gov]

Treatment The provider may recommend the following treatments: Moisturizer Mild steroid creams Medicine, called immunomodulators, applied to the skin to reduce inflammation [account.allinahealth.org]

Pericholangitis

During the past decade, the medical and surgical treatment of ulcerative colitis has undergone dramatic advances, including the widespread use of immunomodulators, biological [books.google.de]

Safety of immunomodulators and biologics for the treatment of inflammatory bowel disease during pregnancy and breast-feeding. [emedicine.medscape.com]

Sympathetic Ophthalmia

With current medical management including corticosteroids and immunomodulators visual prognosis is relatively good. [ncbi.nlm.nih.gov]

[…] ophthalmia following evisceration and discuss the importance of a high degree of clinical suspicion and prompt treatment with high-dose systemic corticosteroids or other immunomodulators [ncbi.nlm.nih.gov]

Along with corticosteroids, immunomodulators such as cyclosporine or azathioprine can be used. [eyewiki.aao.org]

Dermatitis

IgE is increased in individuals with an atopic predisposition Immunomodulators A class of medication that has an effect on the immune system. [doi.org]

Developing Treatments A new class of medications, called topical immunomodulators (TIMs), offers a steroid-free treatment option for treating atopic dermatitis. [childrensnational.org]

Medicines called topical immunomodulators (TIMs) may be prescribed for anyone over 2 years old. [nlm.nih.gov]

Bowel Stenosis

The consultant/authors clearly state their approach to important issues, such as the duration of immunomodulator and of anti-TNF-a use and the options for managing isolated [books.google.com]

Strictures mainly related to inflammation can sometimes be treated with prescription drugs, such as steroids, immunomodulators, and anti-TNF agents. [healthline.com]

C1Q Nephropathy

[…] patient with paroxysmal nocturnal hemoglobinuria. 61 Boqari DT...Alsaad KO 26022031 2015 23 Resolution of C1q deposition but not of the clinical nephrotic syndrome after immunomodulating [malacards.org]