The role of cathelicidin in enabling SCTE-mediated inflammation is verified in mice with a targeted deletion of Camp, the gene encoding cathelicidin.
[ncbi.nlm.nih.gov]
[…] psoriasis Tanel Traks, Maris Keermann, Ele Prans, Maire Karelson, Ulvi Loite, Gea Kõks, Helgi Silm, Sulev Kõks & Külli Kingo BMC Medical Genetics (2019) Cathelicidin promotes inflammation
[doi.org]
[…] cathelicidin peptides found in rosacea, addition of SCTE, and increasing protease activity by targeted deletion of the serine protease inhibitor gene Spink5 each increases inflammation
[ncbi.nlm.nih.gov]