Thrombocytopenia: Causes & Reasons - Symptoma Great Britain

Possible Causes for Thrombocytopenia

Thrombocytopenias, Thrombopenia, Thrombopenias, THROMBOCYTOPENIA, THROMBOPENIA, Thrombocytopenia, unspecified, thrombocytopenia (diagnosis), thrombocytopenia, Thrombocytopaenia [fpnotebook.com]

[…] syndrome SLFN14-related thrombocytopenia Stormorken syndrome TRPM7-related thrombocytopenia Thrombocytopenia absent radius syndrome Tropomyosin 4-related thrombocytopenia [en.wikipedia.org]

Thrombocytopenia NOS, Thrombocytopenia [Disease/Finding], reduced platelet count, Thrombocytopenia NOS (disorder), Thrombocytopenia (disorder), Platelet count decreased, [fpnotebook.com]

Infectious Mononucleosis

They include Granulocytopenia Thrombocytopenia Hemolytic anemia Transient mild granulocytopenia or thrombocytopenia occurs in about 50% of patients; severe cases, associated [merck.com]

Consider corticosteroids for complications such as impending airway obstruction, severe thrombocytopenia, and hemolytic anemia. Click here for Patient Education [msdmanuals.com]

Consider corticosteroids for complications such as impending airway obstruction, severe thrombocytopenia, and hemolytic anemia. [merck.com]

Disseminated Intravascular Coagulation

Splenic sequestration Vitamin K deficiency Heparin-induced thrombocytopenia Background Epidemiology Incidence – >18/100,000 person-years (Singh, 2013) May occur in 30-50% [arupconsult.com]

Severe, rapidly evolving DIC, in contrast, causes thrombocytopenia, depletion of plasma coagulation factors and fibrinogen, and bleeding. [merckmanuals.com]

Laboratory features include thrombocytopenia, reduced levels of fibrinogen and other coagulation factors (leading to prolonged partial thromboplastin, prothrombin, and thrombin [accessmedicine.mhmedical.com]

Aplastic Anemia

After the initial appearance of AMI approximately 2 months earlier, he had received conservative treatment/transfusion alone because of severe thrombocytopenia and anemia [ncbi.nlm.nih.gov]

In women, this can lead to menorrhagia secondary to thrombocytopenia which may require treatment depending on its severity. [ncbi.nlm.nih.gov]

Symptoms result from anemia, thrombocytopenia (petechiae, bleeding), or leukopenia (infections). [merckmanuals.com]

Leukoerythroblastic Anemia

Acute Erythroblastic Leukemia + Anemia, X-Linked, without Thrombocytopenia aplastic anemia + Aplastic Anemia, Idiopathic Bone Marrow Failure Syndromes + chronic myeloid leukemia [rgd.mcw.edu]

[…] who presented seven years following apparently successful surgery and adjuvant chemo-radio-therapy, with blood film findings of microangiopathic hemolytic anemia (MAHA), thrombocytopenia [ncbi.nlm.nih.gov]

If the thrombocytopenia is addressed on admission, such as with the administration of platelets, then code 287.4 would be the principal followed by code 284.89. [hcpro.com]

Myelodysplasia

Presentation on theme: "Thrombocytopenia Scott Akin, MD. Thrombocytopenia Scott Akin, MD. [slideplayer.com]

Abstract Acquired amegakaryocytic thrombocytopenia (AAT) is a rare disease characterized by severe thrombocytopenia due to selective reduction or absence of megakaryocytes [ncbi.nlm.nih.gov]

Keywords: Acquired amegakaryocytic thrombocytopenia, Myelodysplastic syndrome. [tjh.com.tr]

Kasabach-Merritt Syndrome

Approximate Synonyms Amegakaryocytic thrombocytopenia Cyclic thrombocytopenia Kasabach Merritt syndrome Kasabach-Merritt syndrome Mediterranean thrombocytopenia Megakaryocytic [icd9data.com]

Thrombocytopenia-Hemangioma Syndrome — Syndrome, Thrombocytopenia-Hemangioma — Syndromes, Thrombocytopenia-Hemangioma — Thrombocytopenia Hemangioma Syndrome — Thrombocytopenia-Hemangioma [mesh.kib.ki.se]

The combination of vascular tumor and consumptive thrombocytopenia defines KMS. [bionity.com]

Lupus Erythematosus

A 39-year-old woman with Graves’ disease was admitted with anemia and thrombocytopenia. [ekjm.org]

[…] autoimmune thrombocytopenia). [merckmanuals.com]

Hematologic manifestations include anemia (autoimmune hemolytic), leukopenia (usually lymphopenia, with < 1500 cells/mcL), and thrombocytopenia (sometimes life-threatening [msdmanuals.com]

HELLP Syndrome

Criteria developed at the University of Mississippi, as of 2006: "For a patient to merit a diagnosis of HELLP syndrome, class 1 requires severe thrombocytopenia (platelets [clinicaltrials.gov]

Recently 3 women in whom eclampsia was associated with intravascular hemolysis, thrombocytopenia and clotting defects were studied. [doi.org]

"Preeclampsia/eclampsia with hemolysis, elevated liver enzymes, and thrombocytopenia". Obstet Gynecol. 66 (5): 657–60. [en.wikipedia.org]

Chronic Immune Thrombocytopenic Purpura

Immune thrombocytopenia (ITP) care at Mayo Clinic April 30, 2019 References Immune thrombocytopenia. [mayoclinic.org]

Abstract Immune thrombocytopenia (ITP) is a common hematologic disorder. [ncbi.nlm.nih.gov]

Immune thrombocytopenia (adult). Rochester, Minn.: Mayo Foundation for Medical Education and Research; 2019. Immune thrombocytopenia (ITP). [mayoclinic.org]

Portal Cirrhosis

Of the 12 patients with impaired aggregation, 6 had elevated levels of fibrinogen-fibrin degradation products (FDPs), 11 had thrombocytopenia, 10 had shortened euglobulin [ncbi.nlm.nih.gov]

[…] syndrome involves long-term persistence of serum antiphospholipid antibodies and hypercoagulability manifested by venous or arterial thrombosis, recurrent pregnancy loss or thrombocytopenia [adudspace.adu.edu.tr]

Portal hypertensive gastric and duodenal polyps were frequently observed and were associated with thrombocytopenia (p = 0.040; OR: 2.4, 95% CI 1.04–5.50), Child-Pugh score [hindawi.com]

Evans Syndrome

Determination of autoimmune hemolytic anemia or thrombocytopenia or both (Evans syndrome) in Saudi women with antiphospholipid antibody associated recurrent miscarriage 3 [omicsonline.org]

Laboratory tests revealed anemia and thrombocytopenia. Diagnostic tests were performed. [blogs.nejm.org]

From Wikidata Jump to navigation Jump to search Human disease (Thrombocytopenia: [primary] or [idopathic purpuric] or [idiopathic] or [purpuric]) or (Evan's syndrome) Evans [wikidata.org]

Chronic Lymphocytic Leukemia

There is no or little evidence of anemia or thrombocytopenia. [symptoma.com]

Anemia and thrombocytopenia are the major adverse prognostic variables. CLL has no standard staging system. [web.archive.org]

Both substances are alkylating agents with fewer side effects like granulocyto- or thrombocytopenia. [lecturio.com]

Drug-Induced Bone Marrow Suppression

(Also known as/Synonyms) DIT (Drug-Induced Thrombocytopenia) Medication-Induced Thrombocytopenia What is Drug-Induced Thrombocytopenia? [dovemed.com]

[…] drug-induced thrombocytopenia. [spandidos-publications.com]

The phenytoin was replaced by carbamazepine and the patient subsequently developed erythroid hypoplasia, neutropenia and persistent thrombocytopenia. [karger.com]

Immune Thrombocytopenic Purpura

For patient education information, see the Thrombocytopenia Directory Background Immune thrombocytopenia (ITP) was previously known as idiopathic thrombocytopenic purpura. [emedicine.medscape.com]

[…] purpura (TTP), inherited thrombocytopenia, and leukemia. [msdmanuals.com]

(ITP) is a bleeding disorder caused by thrombocytopenia not associated with a systemic disease. [merckmanuals.com]

Autoimmune Thrombocytopenia

Nonemergent Thrombocytopenia DRUG-INDUCED THROMBOCYTOPENIA One of the most common types of thrombocytopenia in the outpatient setting is drug-induced thrombocytopenia. [aafp.org]

Autoimmune thrombocytopenia has been rarely reported in WM and its incidence is not known. [ncbi.nlm.nih.gov]

Thrombocytopenia in pregnancy What every physician needs to know: Thrombocytopenia can be seen in 5 to 10% of all pregnancies. [cancertherapyadvisor.com]

Primary Myelofibrosis

Six weeks later, he developed grade 4 thrombocytopenia and grade 3 anemia. [ncbi.nlm.nih.gov]

The main adverse effects of ruxolitinib are anemia and thrombocytopenia. [merck.com]

Severe side effects resulting from this therapy, such as leukocytopenia or thrombocytopenia, were never observed. [ncbi.nlm.nih.gov]

Amegakaryocytic Thrombocytopenia

Congenital amegakaryocytic thrombocytopenia (CAMT) and thrombocytopenia with absent radii (TAR) share features of isolated thrombocytopenia, reduced or absent marrow megakaryocytes [ncbi.nlm.nih.gov]

Two well-described inherited thrombocytopenia syndromes that present in the newborn period are congenital amegakaryocytic thrombocytopenia (CAMT) and thrombocytopenia with [ncbi.nlm.nih.gov]

CAMT AMEGAKARYOCYTIC THROMBOCYTOPENIA, CONGENITAL Thrombocytopenia congenital amegakaryocytic edit English congenital amegakaryocytic thrombocytopenia thrombocytopenia characterized [wikidata.org]

Heparin-Induced Thrombocytopenia

IIb/IIIa inhibitors, the rate of moderate thrombocytopenia is 4.2% and of severe thrombocytopenia, 1%. 58 Unlike HIT, if thrombocytopenia has been caused by glycoprotein [revespcardiol.org]

Thrombocytopenia The cardinal manifestation of HIT is the occurrence of thrombocytopenia, which occurs in ∼95% patients in temporal association with heparin therapy. 72 Thrombocytopenia [bloodjournal.org]

Heparin-Induced Thrombocytopenia. Medscape. Aug 2014 29. THANK YOU [slideshare.net]

Systemic Lupus Erythematosus

Blood platelet counts (BPCs) of ≤20 × 10/L represent severe thrombocytopenia, and a BPC of 21 to 50 × 10/L indicates moderate thrombocytopenia. [ncbi.nlm.nih.gov]

Background While thrombopoeitin (TPO) agonists that act to simulate platelet production have been approved for use in steroid-refractory chronic immune thrombocytopenia purpura [ncbi.nlm.nih.gov]

Acalculous cholecystitis and thrombocytopenia were initially suspected to be complicated with SLE and vasculitis. [ncbi.nlm.nih.gov]

Thrombocytopenia Due to Sequestration

In this topic Thrombocytopenia Due to Splenic Sequestration Increased splenic platelet sequestration can occur in various disorders that cause Splenomegaly However, thrombocytopenia [univadis.co.uk]

[…] describes a case of hemangioma associated with thrombocytopenia in a 7-day-old infant. [jamanetwork.com]

Paroxysmal Nocturnal Hemoglobinuria

This case raises caution for heparin-induced thrombocytopenia in paroxysmal nocturnal hemoglobinuria. [ncbi.nlm.nih.gov]

The combination of thrombosis, splenomegaly, and thrombocytopenia (TST) is challenging because anticoagulants are indicated but thrombocytopenia may increase the bleeding [ncbi.nlm.nih.gov]

The patient's anticoagulation was complicated by heparin-induced thrombocytopenia (HIT) highlighting the unique management challenge presented by PNH in combination with HIT [ncbi.nlm.nih.gov]

Gaucher Disease

KEYWORDS: GBA gene mutation; Gaucher cells; thrombocytopenia; type 1 Gaucher disease [ncbi.nlm.nih.gov]

Symptoms of the disease may include enlargement of the spleen and liver (a big belly or abdomen), anemia, thrombocytopenia (low platelet counts), bone pain, and bone fragility [thinkgenetic.com]

A patient known for hepatosplenomegaly with hyperferritinemia, anemia, and thrombocytopenia was admitted for Lewy body dementia and bullous pemphigoid. [ncbi.nlm.nih.gov]

Philadelphia Chromosome-Positive Chronic Myeloid Leukemia

Multivariate analysis only identified 2 significant prognostic features: thrombocytopenia and more than 5% peripheral blasts. [ncbi.nlm.nih.gov]

Grade 3 or 4 hematologic abnormalities by treatment group included thrombocytopenia, neutropenia, and anemia in 36%, 24%, and 14% of chronic-phase CML patients; 47%, 51%, [ascopost.com]

Univariate analysis identified 4 poor prognostic features: thrombocytopenia, more than 5% peripheral blasts, more than 5% erythroid precursors and less than 7 g/dl of hemoglobin [ncbi.nlm.nih.gov]

Secondary Myelofibrosis

Severe anemia and thrombocytopenia with leukoerythroblastosis were prominent clinical features in all six patients. [ncbi.nlm.nih.gov]

Moreover, its use is often hampered by side effects, including both anemia and thrombocytopenia. [consultqd.clevelandclinic.org]

Bone marrow failure eventually occurs, with consequent anemia and thrombocytopenia. [slideshare.net]

Exchange Transfusion

(platelet count CONCLUSION: ET in neonates with HDFN is associated with an increased risk of sepsis, leukocytopenia, thrombocytopenia, hypocalcemia and hypernatremia. [ncbi.nlm.nih.gov]

The most common encountered complications of ET procedure were hyperglycemia (56.5%), hypocalcaemia (22.5%) and thrombocytopenia (16%). [ncbi.nlm.nih.gov]

(n = 2), hypocalcemia and thrombocytopenia (n = 1), and hyponatremia and thrombocytopenia (n = 1). [pediatrics.aappublications.org]

Primary Immune Deficiency Disorder

In other patients – adults as well as children and infants – weight loss, chronic gastrointestinal infections, and autoimmune disease such as immune thrombocytopenia, hemolytic [mountsinai.org]

[…] association with CVID. [30] Autoimmune phenomena As many as 20% of patients with CVID develop autoimmune complications. [1] Rheumatoid arthritis, vitiligo, hemolytic anemia, thrombocytopenia [emedicine.medscape.com]

The associated conditions in PID individuals may present in a single tissue or organ, such as autoimmune hemolytic anemia, thrombocytopenia, and autoimmune thyroiditis, or [intechopen.com]

Post-Polycythemia Vera Myelofibrosis

This case suggests that ruxolitinib is a treatment option for post-PV MF in patients with thrombocytopenia or JAK2 exon 12 mutations. [ncbi.nlm.nih.gov]

Pacritinib Versus Physician's Choice in Patients With Primary Myelofibrosis, Post Polycythemia Vera Myelofibrosis, or Post-Essential Thrombocythemia Myelofibrosis With Severe Thrombocytopenia [canadiancancertrials.ca]

We describe how treatment with a JAK1/2 inhibitor, ruxolitinib, led to the rapid amelioration of marrow fibrosis, erythrocytosis and thrombocytopenia in a 77-year-old man [ncbi.nlm.nih.gov]

Glanzmann Thrombasthenia

Free Case Reports | June 2002 Use of Recombinant Factor VIIa (NovoSeven®) to Reduce Postoperative Bleeding after Total Hip Arthroplasty in a Patient with Cirrhosis and Thrombocytopenia [anesthesiology.pubs.asahq.org]

Heikal, Rare complication of treated immune thrombocytopenia, American Journal of Hematology, 92, 11, (1262-1266), (2017). John E. Zvijac, Sharhabil S. [doi.org]

Acquired GT is usually accompanied by thrombocytopenia [6]. [link.springer.com]

Familial Myelofibrosis

Here we describe 3 families with inherited thrombocytopenia and cMF due to germline null mutations in the megakaryocyte-specific immunoreceptor tyrosine-based inhibitory motif [ashpublications.org]

Blood counts generally reveal normocytic, normochromic anemia, leukopenia, and thrombocytopenia. [symptoma.com]

[…] thrombocytosis, increased LDH Prognostic factors Histologic stage at diagnosis (prefibrotic versus fibrotic) Adverse factors include age > 70 years, anemia (Hb < 10 g/dL), thrombocytopenia [pathologyoutlines.com]